BACKGROUND:
AMS Laboratories are able to perform antibiotic potency testing by the bioassay method. Antibiotic potency is estimated by comparing the inhibition of growth of sensitive micro-organisms produced by known concentrations of the antibiotic being examined against a reference standard substance. The test is performed on raw materials and finished products to confirm the antibiotic activity meets specifications.
PRINCIPLE OF TEST:
All test methods are based on the European and British Pharmacopeia: Biological assay of antibiotics, BP Appendix XIV A (Ph. Eur. method 2.7.2)
This is a large-plate format procedure where test and standard preparations are loaded into wells in a randomized latin square arrangement before incubation and reading the zones of inhibition.
List of methods/antimicrobials available:
Amphotericin B
Bacitracin
Bleomycin
Colistin 
Colistimethate
Dihydrostreptomycin
Erythromycin
Framycetin
Gentamicin
Kanamycin
Neomycin
Netilmicin
Nystatin
Polymyxin B
Rifamycin
Spiramycin
Streptomycin
Tobramycin
Tylosin
Vancomycin
We can also perform Antimicrobial Activity Tests such as the
Minimum Inhibition Concentration (MIC) Test
Minimum Bactericidal Concentration (MBC) Test
Minimum Kill Concentration ( MKC) Test
Zone of Inhibition (ZOI) Test
SAMPLE REQUIREMENTS and TURNAROUND TIMES:
AS these will vary with the type of product and study required, please contact the laboratory to discuss your needs.